Patient Enrollment
Get patients started with EntyvioConnect
Complete the enrollment form together and fax to 1‑877‑488‑6814.
Connect with your Field Access Manager (FAM) or call 1-855-ENTYVIO (1-855-368-9846) to speak with a Case Manager, Monday to Friday, from 8 am to 8 pm ET (except holidays).
Financial Support
Connect to Savings
ENTYVIO Co-Pay Assistance Program can help eligible patients with commercial insurance pay as little as $0 per dose of ENTYVIO up to a total benefit of $20,000 per year.†
Connect to Treatment
Start Program can help your eligible commercial patients start on ENTYVIO fast during insurance delays for $0 up to 3 years.†
Bridge Program helps your commercial patients stay on track at no cost during gaps in insurance coverage for up to 6 months.†
ENTYVIO Patient Assistance Program (PAP) helps patients with no health insurance or those whose benefits are insufficient to cover the cost of ENTYVIO and there is an identified financial need.†
†Terms and conditions apply. Must meet eligibility requirements.
The EntyvioConnect Co-Pay Program (“Co-Pay Program”) provides financial support for commercially insured patients who qualify for the Co-Pay Program. Participation in the Co-Pay Program and provision of financial support is subject to all Co-Pay Program terms and conditions, including but not limited to eligibility requirements, the maximum benefit per claim, and the Maximum Annual Benefit. By enrolling in the Co-Pay Program, you agree that the program is intended solely for the benefit of you—not health plans and/or their partners. Further, you agree to comply with all applicable requirements of your health plan. The Co-Pay Program cannot be used if the patient is a beneficiary of, or any part of the prescription is covered by: 1) any federal, state, or government-funded healthcare program (Medicare, Medicare Advantage, Medicaid, TRICARE, etc.), including a state pharmaceutical assistance program (the Federal Employees Health Benefit (FEHB) Program is not a government-funded healthcare program for the purpose of this offer), 2) the Medicare Prescription Drug Program (Part D), or if the patient is currently in the coverage gap, or 3) insurance that is paying the entire cost of the prescription. Takeda reserves the right to change or end the Co-Pay Program at any time without notice, and other terms and conditions may apply.
If you have enrolled in an accumulator adjustment, co-pay maximizer, or similar program that purports to help manage costs or later learn that your insurance company or health plan has implemented such a program, you agree to inform EntyvioConnect at 1-844-368-9846. In an accumulator adjustment program, payments made by you that are subsidized by a manufacturer co-pay assistance program do not count toward your deductibles and other out-of-pocket cost-sharing obligations. In a co-pay maximizer program, the amount of your out-of-pocket cost obligation is increased to match support offered by a manufacturer co-pay assistance program. It may be possible that you are unaware whether you are subject to these programs when you enroll in the Co-Pay Program. Takeda will monitor program utilization data and reserves the right to discontinue assistance under the Co-Pay Program at any time if Takeda determines that you are subject to a co-pay maximizer, accumulator, or similar program.
The Maximum Annual Benefit under the Co-Pay Program is subject to change without notice. Subject to all terms and conditions, the Maximum Annual Benefit under the Co-Pay Program may be applied to out-of-pocket cost for your ENTYVIO prescription, including co-pay, co-insurance or deductible. The Co-Pay Program is for medication costs only and does not include costs to give you your treatment. Subject to all terms and conditions, the Maximum Annual Benefit under the Co-Pay Program is $20,000 per calendar year. However, except where prohibited by law, if your insurance company or health plan implements a co-pay maximizer program or similar program, you will have a reduced Maximum Annual Benefit of $9,000 per calendar year. If your insurance company or health plan removes ENTYVIO from such program, subject to all terms and conditions, you will be eligible for co-pay assistance up to the Maximum Annual Benefit for patients who are not subject to maximizer adjustment or similar programs.
The actual application and use of the benefit available under the co-pay assistance program may vary on a per-claim, monthly, quarterly, and/or annual basis, depending on each individual patient’s health plan and other prescription drug costs.
Patient may not seek reimbursement from any other plan or program (Flexible Spending Account [FSA], Health Savings Account [HSA], Health Reimbursement Account [HRA], etc.) for any out-of-pocket costs covered by the Co-Pay Program. Patient or healthcare provider may be required to submit an Explanation of Benefits (EOB) following each infusion to the Co-Pay Program.
The Co-Pay Program only applies in the United States, including Puerto Rico and other U.S. territories, and does not apply where prohibited by law, taxed, or restricted. This does not constitute health insurance. Void where use is prohibited by your insurance provider or health plan. If your health plan changes you must notify EntyvioConnect at 1-844-368-9846. This offer is not transferable and is limited to one offer per person and may not be combined with any other coupon, discount, prescription savings card, rebate, free trial, patient assistance, co-pay maximizer, alternative funding program, co-pay accumulator, or other offer, including those from third parties and companies that help insurers or health plans manage costs. Not valid if reproduced.
By utilizing the Co-Pay Program, you hereby accept and agree to abide by these terms and conditions. Any individual or entity who enrolls or assists in the enrollment of a patient in the Co-Pay Program represents that the patient meets the eligibility criteria and other requirements described herein. You must meet the program eligibility requirements every time you use the program.
Resources
Insurance Support
Connect to Coverage
ENTYVIO has broad, unrestricted commercial coverage for your patients.‡
‡For IV, unrestricted refers to coverage that does not require biologic step-edits. For pen, covered commercial lives include unrestricted coverage and biologic step-edits. Data are derived from Managed Markets Insight & Technology as of December 2025.
Contact an EntyvioConnect Case Manager at 1-855-ENTYVIO (1-855-368-9846), Monday to Friday, from 8 am to 8 pm ET (except holidays).
Insurance Approvals
EntyvioConnect offers your patients support throughout the entire insurance approval process.
Resources
Reimbursement
Utilize these resources when submitting reimbursement claims for your patients.
Resources
Dedicated 1:1 Support
Designed with your patients in mind
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The content on this page has been written and reviewed by Takeda.