For adult patients with moderately to severely active UC or CD when other therapies have not worked well enough or cannot be tolerated.
Once your patients have been prescribed Entyvio, EntyvioConnect can partner with them at every step of the insurance approval process. The following support services are available to help patients gain access to Entyvio:
- Benefits investigation
- Prior authorization information and support
- Denials and appeals support
What if my patient doesn't have insurance or is denied coverage?
EntyvioConnect offers 2 programs that may help with continued access in case more time is needed for coverage approval.
Start Program*: New-to-Entyvio patients who have received a denied prior authorization from a commercial health plan are eligible
- Entyvio may be provided at no cost for up to 1 year while the appeals process is conducted
- Evidence of appeal activity must be sent to EntyvioConnect throughout the year
Bridge Program*: Entyvio patients with a temporary loss or gap in commercial coverage are eligible
- Provides Entyvio at no cost for up to 6 months
- After 6 months, EntyvioConnect will look for available coverage assistance programs if needed
*Additional terms and conditions may apply
You can speak directly to
a Patient Support Manager for
more information at 1‑855‑ENTYVIO
Monday to Friday, from 8 am to 8 pm ET (except holidays).
Download resources for insurance support
These resources are provided for informational purposes only and are not intended to provide reimbursement or legal advice. Contact third-party payers for specific information on their current coverage, reimbursement, and coding policies.
EntyvioConnect At a Glance
EntyvioConnect offers your patients support throughout the entire insurance approval process.
Important Safety Information
- ENTYVIO (vedolizumab) for injection is contraindicated in patients who have had a known serious or severe hypersensitivity reaction to ENTYVIO or any of its excipients.
- Infusion-related reactions and hypersensitivity reactions including anaphylaxis, dyspnea, bronchospasm, urticaria, flushing, rash, and increased blood pressure and heart rate have been reported. These reactions may occur with the first or subsequent infusions and may vary in their time of onset from during infusion or up to several hours post-infusion. If anaphylaxis or other serious infusion-related or hypersensitivity reactions occur, discontinue administration of ENTYVIO immediately and initiate appropriate treatment.
- Patients treated with ENTYVIO are at increased risk for developing infections. Serious infections have been reported in patients treated with ENTYVIO, including anal abscess, sepsis (some fatal), tuberculosis, salmonella sepsis, Listeria meningitis, giardiasis, and cytomegaloviral colitis. ENTYVIO is not recommended in patients with active, severe infections until the infections are controlled. Consider withholding ENTYVIO in patients who develop a severe infection while on treatment with ENTYVIO. Exercise caution in patients with a history of recurring severe infections. Consider screening for tuberculosis (TB) according to the local practice.
- Progressive multifocal leukoencephalopathy (PML), a rare and often fatal opportunistic infection of the central nervous system (CNS), has been reported with systemic immunosuppressants, including another integrin receptor antagonist. PML is caused by the John Cunningham (JC) virus and typically only occurs in patients who are immunocompromised. One case of PML in an ENTYVIO-treated patient with multiple contributory factors has been reported in the post marketing setting (e.g., human immunodeficiency virus [HIV] infection with a CD4 count of 300 cells/mm3 and prior and concomitant immunosuppression). Although unlikely, a risk of PML cannot be ruled out. Monitor patients for any new or worsening neurological signs or symptoms. Typical signs and symptoms associated with PML are diverse, progress over days to weeks, and include progressive weakness on one side of the body or clumsiness of limbs, disturbance of vision, and changes in thinking, memory, and orientation leading to confusion and personality changes. If PML is suspected, withhold dosing with ENTYVIO and refer to a neurologist; if confirmed, discontinue ENTYVIO dosing permanently.
- There have been reports of elevations of transaminase and/or bilirubin in patients receiving ENTYVIO. ENTYVIO should be discontinued in patients with jaundice or other evidence of significant liver injury.
- Prior to initiating treatment with ENTYVIO, all patients should be brought up to date with all immunizations according to current immunization guidelines. Patients receiving ENTYVIO may receive non-live vaccines and may receive live vaccines if the benefits outweigh the risks.
- Most common adverse reactions (incidence ≥3% and ≥1% higher than placebo): nasopharyngitis, headache, arthralgia, nausea, pyrexia, upper respiratory tract infection, fatigue, cough, bronchitis, influenza, back pain, rash, pruritus, sinusitis, oropharyngeal pain, and pain in extremities.
Adult Ulcerative Colitis (UC)
ENTYVIO (vedolizumab) is indicated in adults for the treatment of moderately to severely active UC.
Adult Crohn's Disease (CD)
ENTYVIO (vedolizumab) is indicated in adults for the treatment of moderately to severely active CD.